Comecer Radiation Protection Equipment, Hot Cells and Aseptic Isolators
Industrial catalogue of Comecer equipment (Italy): BBS and BBST shielded hot cells, Theodorico 2 robotic dispensers, Iris multidose injectors, Flexline aseptic filling systems, and Speedy Glove testers.
BBS and BBST Shielded Hot Cells for Radiopharmacy
Shielded hot cells of the BBS and BBST series enable safe radiopharmaceutical synthesis and dispensing. Work chambers integrate 50 or 75 mm lead protection with Grade A laminar airflow. The AISI 316L stainless steel enclosure ensures containment integrity compliant with ISO 10648-2.
- Continuous radiation shielding with 50 mm or 75 mm lead equivalence
- Laminar airflow Grade A cleanroom environment compliant with ISO 10648-2
- Full integration with Taddeo, GE, Trasis and IBA radiochemistry synthesis units
- Replacement lead glass panes, Hypalon glove ports, seals and HEPA filters
Theodorico 2 Robotic Dispensers for Radiopharmaceuticals
The Theodorico 2 robotic system performs automated filling of radiopharmaceuticals into vials. Operating inside a Grade A shielded chamber, the platform achieves dispensing accuracy within two percent. An integrated ionization chamber interface verifies dose radioactivity for each vial.
- Precision peristaltic and syringe dispensing with volume accuracy within two percent
- Automated rubber stoppering and aluminum crimping inside shielded enclosure
- Seamless interface with VDC-606 dose calibrators and IBC management software
- Interchangeable fluid dispensing lines, needles, gripper fingers and servomotors
Iris Automated Radiopharmaceutical Multidose Injectors
The Iris mobile injector provides calibrated administration of radiopharmaceuticals for PET diagnostic protocols. Heavy tungsten shielding reduces staff radiation exposure by over ninety-nine percent. An autonomous motorized drive ensures smooth positioning across clinical departments.
- Tungsten shielding structure reducing operator radiation exposure by over 99%
- Precise automated dose fractionation of 18F-FDG solutions prior to patient delivery
- Battery powered mobile chassis with electric motor drive and touch control screen
- Sterile single use injection administration sets, check valves and tungsten shields
Flexline Robotic Aseptic Filling and Closing Lines
Flexline systems execute aseptic filling and closing of ready to use vials, syringes, and cartridges. The isolation barrier incorporates an integrated VPHP vaporized hydrogen peroxide generator for biodecontamination. Robotic arms prevent mechanical particle generation in critical zones.
- Processing ready to use RTU nested vials, prefilled syringes and cartridges
- Built-in automated VPHP vaporized hydrogen peroxide decontamination cycle
- Cleanroom Grade A airflow compliant with EU GMP Annex 1 sterile manufacturing
- Peristaltic pump heads, ceramic rotary pistons, filling needles and robot grippers
Speedy Glove Automatic Portable Glove Integrity Testers
The Speedy Glove portable tester verifies glove integrity on isolators and hot cells via pressure decay. Testing completes in under three minutes in compliance with ISO 14644-7 methodology. A wireless communication module uploads test records to audit trails compliant with 21 CFR Part 11.
- Automated pressure decay testing methodology compliant with ISO 14644-7
- Rapid automated measurement test sequence completing in under three minutes
- Wireless digital data transfer and audit trail compliant with 21 CFR Part 11
- Inflatable sealing rings, micro pneumatic valves, batteries and pressure sensors
VDC-606 Touch Screen Dose Calibrators and Radiation Monitors
The VDC-606 dose calibrator utilizes a pressurized ionization chamber for rapid isotope activity quantification. A color touch screen displays radioisotope activity and automatically corrects for radioactive decay. The unit interfaces with clinic networks through standard TCP/IP protocols.
- Well type high pressure argon ionization chamber with 4 Pi geometry
- Radioactivity measurement range up to 74 GBq for PET and SPECT radionuclides
- Isotope library with automatic background subtraction and decay correction
- Sample well liners, dipper holders for vials and syringes, and shielded cables
Shielded Hot Cell Configuration for Radiopharmaceutical Synthesis
Selecting BBS and BBST series shielded hot cells involves matching lead shielding thickness, internal chamber volume, and remote manipulator layouts to target isotope energy spectra.
For positron emitters such as carbon-11 and fluorine-18 emitting 511 keV annihilation photons, 75 mm lead shielding provides adequate radiation attenuation, whereas therapeutic beta emitters like lutetium-177 operate within 50 mm lead enclosures.
Electropolished AISI 316L stainless steel chambers facilitate rapid decontamination, while negative pressure air handling ensures containment of airborne radioisotopes.
Integration of Flexline Aseptic Filling Platforms with VPHP Decontamination
Modular Flexline robotic filling platforms address sterile packaging of small to medium clinical batches of radiopharmaceuticals and biological therapeutics.
Multi-axis robotic arms operating within barrier isolators eliminate human intervention in Grade A critical areas, preventing particulate contamination.
The integrated VPHP cycle vaporizes hydrogen peroxide to achieve a six-log reduction in bioburden without exposing heat sensitive drug formulations or machine electronics to thermal degradation.
Comecer / Comecer S.p.A. and model names are trademarks of their respective owners and are used only to identify the equipment for which we source parts. SpareX is not an official dealer, distributor or representative of Comecer / Comecer S.p.A. and is not affiliated with the trademark owner. Origin, documents and warranty are stated for each item in the quotation.
Related equipment manufacturers
- Equipment and parts for Logics & Controls
- Equipment and parts for Spencer Turbine
- Equipment and parts for L.A. Turbine
- Equipment and parts for Hudson Products
Documents and sources
- Official Comecer portal — aseptic processing and containment systems
- Full Comecer product catalogue — hot cells and isolator systems
- About Comecer — company background and ATS Life Sciences group
- Comecer validation protocols — FAT, SAT, IQ and OQ under GMP guidelines
- Comecer service and maintenance solutions for containment equipment
- Comprehensive Comecer services and industrial technical support
- Comecer quality management system — ISO 9001 and ISO 13485 standards
