LYOMAC Industrial, Pilot and Lab Freeze Dryers

Selection and quotation of LYOMAC equipment: industrial, pilot, lab and benchtop LYOPRO lyophilizers, LMF food freeze dryers, ALAUS loading systems and turnkey lyophilization lines for vials and bulk materials.

LYOPRO-10.0 to 50.0 Industrial Freeze Dryers

Production lyophilizers built to cGMP, FDA, EU PED and GAMP5 for vials, pre-filled syringes and bulk materials. Ice capacity runs from 200 to 1000 kg, the inner chamber is 316L stainless steel, with built-in CIP/SIP and automatic shelf stoppering under vacuum.

Ice capacity: 200-1000 kg
Shelf area: 9.72-49.50 m²
Condenser: down to -75 °C
Ultimate vacuum: ≤1.0 Pa

LYOPRO-1.0 to 7.5 Pilot Freeze Dryers

The bridge between lab units and industrial dryers for formulation work, cycle verification and trial batches. Drying capacity is 20 to 150 L, with automatic vacuum stoppering, CIP and SIP, and a GAMP5 SCADA system that stores thousands of recipes.

Drying capacity: 20-150 L
Shelf area: 1.08-7.56 m²
Shelf flatness: ≤1.0 mm
Power: 18-52 kW

LYOPRO-0.2 to 0.6 Lab Freeze Dryers

Compact units for university labs, biotech R&D centers and pharma formulation labs. Sample contact parts are 316L stainless steel, a PLC touchscreen runs the cycle and records full-cycle data. Lab parameters scale up directly to LYOMAC pilot and industrial dryers.

Drying capacity: 4-12 L
Shelf temperature: -55 to +70 °C
Uniformity: ±0.5 °C
Power: 4-8 kW

Benchtop Freeze Dryers

A desktop unit for formulation screening and small samples: the transparent glass cover shows sublimation without breaking vacuum. Freezing and drying run on the same in-situ shelf, and vials are stoppered by a manual top press inside the chamber. Loads trays, vials or manifold flasks.

Cover: transparent glass
Shelf: in-situ freezing and drying
Stoppering: manual top press
Vials: 5, 10 and 30 ml

LMF-5 to LMF-50 Food Freeze Dryers

Conductive dryers for fruit, vegetables, probiotics and food ingredients: freezing and drying run in one chamber on the same shelves. Heating is electric with full PID control, the build is SUS304 stainless steel, and the whole system is remote controlled from a PC.

Capacity: 50-500 kg
Trays: 45-342 pcs
Heating: electric
Power: 40-215 kW

LMF-60 to LMF-200 Radiant Freeze Dryers

A line of a blast freezer and a freeze dryer: product is frozen separately and moved into the chamber on trolleys along an overhead monorail. Steam is the heating source, and anodized aluminum shelves keep temperature uniform and radiation efficient.

Capacity: 600-2000 kg
Steam use: 180-600 kg/h
Trolleys: 2-7 sets
Power: 118-461 kW

ALAUS Loading and Unloading Systems

Automatic loading for industrial dryers to GMP and FDA, for sterile vials and bulk materials, with every moving system driven by servo motors. The fixed system moves vials row by row from filler to pizza door and on to the capper; trays use an AGV or fixed tray loader.

Drive: servo motors
Vials: row by row
Trays: AGV or fixed loader
Isolation: isolator or RABS

Turnkey Lyophilization Lines

Two full-process lines. For vials: washing, tunnel sterilization and depyrogenation, filling with half stoppering, auto loading, drying with full stoppering and capping. For APIs and probiotics: liquid preparation, dosing, freeze drying and discharging.

Washing: ultrasonic
Sterilization: tunnel oven
Filling: with half stoppering
Finish: vial capping

Choosing the Scale: Lab, Pilot, Production

LYOPRO-0.2 to 0.6 lab units with 4-12 L drying capacity work out formulations and drying curves, while benchtop models with a glass cover screen small samples.

LYOPRO-1.0 to 7.5 pilot dryers, 20-150 L, verify cycles and run trial batches; LYOPRO-10.0 to 50.0 industrial dryers with 200-1000 kg ice capacity handle commercial output.

Temperature, vacuum and heating control logic is shared across the range, so lab parameters scale up to pilot and industrial units without repeated debugging.

Vial Loading and Shelf Area

Capacity is counted in 16 mm and 22 mm vials: LYOPRO-1.0 holds 4400 or 2200 vials, LYOPRO-7.5 holds 32,000 or 16,000, and the industrial LYOPRO-50.0 holds 200,000 or 100,000. Industrial shelf area is 9.72-49.50 m² with 100 mm between shelves, 90 mm on LYOPRO-40.0 and 50.0.

A 30 ml vial takes about three times the shelf space of a 5 ml vial, so batch size is recalculated for each ISO 8362 vial size.

Food Dryers: Conductive or Radiant

LMF-5 to LMF-50 conductive dryers, 50-500 kg, freeze and dry product in one chamber on the same shelves, with electric PID-controlled heating and a SUS304 build.

LMF-60 to LMF-200 radiant dryers, 600-2000 kg, work with a blast freezer: product moves on trolleys along an overhead monorail, steam at 180-600 kg/h is the heat source, and shelves are anodized aluminum. The dryers serve fruit, vegetables, berries, seafood, probiotics, plant extracts and pet food.

Automation: ALAUS and Turnkey Lines

The ALAUS system loads industrial dryers without operators: the fixed version moves vials row by row from the filler to the pizza door and on to the capper after drying, and trays use an AGV or fixed tray loader, both ready for an isolator or RABS.

The turnkey vial line covers washing, tunnel sterilization, filling with half stoppering, auto loading, drying with full stoppering and capping; the manufacturer supplies IQ, OQ and PQ documents.

LYOMAC and model names are trademarks of their respective owners and are used only to identify the equipment for which we source parts. SpareX is not an official dealer, distributor or representative of LYOMAC and is not affiliated with the trademark owner. Origin, documents and warranty are stated for each item in the quotation.