Filling and closing machines, packaging lines Groninger

Groninger Group automated packaging technology: robocell gloveless aseptic lines, high-speed integra filling suites, modular flexcare machines, and rotary pumps.

Robotic aseptic filling systems Groninger series robocell for RTU containers

Gloveless filling systems Groninger series robocell provide fully automated aseptic processing for nested ready-to-use syringes, vials, and cartridges. Built in strict alignment with Annex 1 guidelines, the machinery maintains unidirectional laminar airflow.

Complete barrier isolation without manual glove interventions during processing
Continuous first air aerodynamic flow profile eliminating air pocket stagnation
Automated routing for single-use filling pathways and PUPSIT filter assemblies
Comprehensive 100 percent in-process weight checking minimizes liquid volume loss

High-speed isolated bulk vial filling lines Groninger series integra

Integrated isolated packaging lines Groninger series integra combine vial washing, depyrogenation tunnels, filling, and stoppering stations operating at speeds up to 24,000 units per hour. The platform processes vial sizes 2R through 100H for 1 to 100 ml fills.

High throughput reaching 24,000 vials per hour for high-capacity batch output
Broad container envelope handling 2R to 100H vials across 1 to 100 ml volumes
Singledisc capping mechanism reduces particulate generation around stoppers
Toolless quickconnect changeover mechanism reduces format switchover intervals

Modular filling and closing systems Groninger series flexcare

Versatile filling machines Groninger series flexcare 10/100/101/200 are tailored for liquid healthcare syrups, nasal sprays, droppers, and topical cosmetics. Delivering throughput up to 7,200 objects per hour, the modules accommodate containers of 16 to 68 mm width.

Operational output up to 7,200 units per hour during automated filling cycles
Container processing range spanning 16 to 68 mm for filling volumes of 1-270 ml
Ergonomic frame architecture without bulky doorways enables rapid sanitation
Seamless fit for rotary stainless pumps supporting CIP and SIP cleaning loops

Precision rotary piston pumps and Single-Use dosing modules Groninger

Patented rotary piston pumps Groninger and disposable Single-Use Rotary Piston Pump units provide steady volumetric dosing for demanding viscous fluids and oily suspensions. Fabricated from 316L/1.4435 stainless steel, units administer precise fills from 0.1 to 2.25 ml.

Consistent volumetric filling of demanding viscous solutions and oil emulsions
Fluid-contact components from 316L/1.4435 stainless steel with finish Ra ≤ 0.8
Single-use dosing assembly rated for a continuous lifespan of 120,000 strokes
Seamless installation onto servo-driven groninger filling stations via adapters

Benchtop filling and closing machines Groninger series labworx for labs

Semiautomated benchtop machines Groninger series labworx are engineered for biotechnology laboratories, pilot batches, and clinical research campaigns. The compact units support peristaltic or rotary piston dosing and closing for vials, nested syringes, and cartridges.

Compact exterior footprint suited for installation inside laminar flow hoods
Direct scalability of filling process parameters to full-scale automated lines
Zero-loss handling of valuable small batches across vials, syringes, and tub RTU
Intuitive touch screen operator panel for rapid recipe loading and validation

Automated vial capping and sealing modules Groninger singledisc

High-precision capping modules Groninger are built for aluminum crimping on pharmaceutical vials with lowest particulate shedding. Patented singledisc rolling technology achieves airtight vial hermetic sealing without shedding aluminum debris in the cleanroom.

Drastic suppression of aluminum dust particles inside sterile cleanroom zones
Precision servo-driven torque control tailored for each individual container
Broad handling of rubber stoppers, flip-off caps, dropper pumps, and screw tops
Integrated vision monitoring verifies stopper seating height and crimp integrity

German engineering traditions and Groninger filling machinery development

The engineering history of Groninger began in 1980 in Crailsheim, Baden-Wuerttemberg, when Horst Groninger founded a specialized manufacturing facility for liquid filling machines.

Over four decades, the family-owned enterprise has evolved into a global technology leader in customized machinery for the pharmaceutical, consumer healthcare, and cosmetics industries.

Today, the Groninger Group employs over 1,700 professionals across advanced manufacturing sites in Crailsheim, Schnelldorf, and Charlotte in the United States.

The corporation develops fully automated filling and closing lines, deploying groundbreaking patents in precision dosing and container conveyance for major multinational biopharmaceutical manufacturers.

Robotic gloveless aseptic filling systems robocell in Annex 1 compliance

The robotic gloveless filling system Groninger series robocell represents a technological milestone in the aseptic processing of pre-sterilized ready-to-use syringes, vials, and cartridges in nested configurations.

Developed in collaboration with cleanroom specialist SKAN, this platform eliminates manual glove ports from the core filling zone entirely.

Removing direct human intervention from the sterile core neutralizes contamination risks during the production of personalized medicines, monoclonal antibodies, and cell therapies.

The robocell architecture adheres strictly to GMP Annex 1 guidelines, featuring unidirectional laminar airflow, automated single-use fluid path exchange, and continuous weight verification.

High-speed isolated bulk vial filling lines series integra for pharmaceuticals

The high-speed isolated packaging line Groninger series integra is engineered for serial bulk processing of liquid injectable solutions in glass vials at speeds up to 24,000 units per hour.

The installation harmoniously integrates rotary ultrasonic washing, a depyrogenation tunnel, isolated filling, and an aluminum vial crimping module into an enclosed system.

Accommodating vial formats from 2R to 100H, the system delivers precise fill volumes from 1 to 100 ml using multi-head rotary piston or peristaltic dosing units.

Patented quickconnect toolless changeover technology curtails downtime between batches, while an ultra-slim table depth provides one-sided access for inspection, wipe-down, and routine sanitation.

Modular filling and closing systems series flexcare for consumer healthcare

Modular filling and closing systems in the Groninger flexcare 10, flexcare 100, flexcare 101, and flexcare 200 series are designed for reliable packaging of non-sterile and low-bioburden liquid products.

The platform is ideally tailored for over-the-counter syrups, nasal and ear sprays, eye drops, nutritional liquids, and dermatological cosmetics.

The flexcare 100 unit delivers operating throughput reaching 7,200 containers per hour for diameters between 16 and 68 mm and fill volumes from 1 to 270 ml. An open frame layout without cumbersome doorway partitions ensures complete line visibility and rapid sanitation.

Stations accommodate 316L stainless rotary pumps supporting CIP washing and SIP steam cycles.

Precision rotary piston pumps and Single-Use disposable dosing pathways

The rotary piston pump is an iconic patented engineering design by Groninger that established modern dosing benchmarks in the global pharmaceutical packaging industry.

Rather than relying on external check valves, the rotary piston performs simultaneous reciprocating and rotational motion, alternating ports without risk of sticking when handling dense liquids.

For advanced bioprocessing, Groninger manufactures Single-Use Rotary Piston Pump assemblies. The disposable 10 mm diameter dosing cartridge delivers fill volumes from 0.1 to 2.25 ml in sterile blister packaging.

Wetted components are crafted from 316L/1.4435 stainless steel with surface finish Ra ≤ 0.8 µm, ensuring an operating lifespan exceeding 120,000 strokes.

Vial sealing and crimping technology with patented singledisc rolling action

Hermetic sealing of pharmaceutical vials with rubber stoppers and aluminum Flip-Off caps represents a crucial step in the final packaging process. Conventional multi-roller crimping heads generate metal-to-metal friction during aluminum skirt deformation, shedding microscopic metal particles.

To solve this, Groninger patented the singledisc crimping system.

Employing a single contoured spinning disc suppresses friction and prevents the release of metallic particles near the vial neck opening.

Each crimping spindle features an independent servo motor monitoring downward pressure and radial crimping torque, while optical sensors and machine vision systems automatically reject vials with imperfect closures.

Groninger and model names are trademarks of their respective owners and are used only to identify the equipment for which we source parts. SpareX is not an official dealer, distributor or representative of Groninger and is not affiliated with the trademark owner. Origin, documents and warranty are stated for each item in the quotation.